TLR4 anticorps (Biotin)

N° du produit ABIN206336

L’anticorps Souris Monoclonal anti-TLR4 a été validé pour WB, FACS et IP. Il convient pour détecter TLR4 dans des échantillons de Humain, Chien, Porc, Cobaye et Macaque rhésus.

Aperçu rapide pour TLR4 anticorps (Biotin) (ABIN206336)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Humain, Chien, Porc, Cobaye, Macaque rhésus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR4 est conjugé à/à la Biotin

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Détail du produit anti-TLR4 anticorps (Biotin)

Specificité: Recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. Has been demonstrated to block activation of monocytes with LPS. XXX recommend the use of MCA2061EL for this purpose.

Purification: Protein G purified

Immunogène: Ba/F3 cell line expressing TLR4 (CD284).

Isotype: IgG2a

Information d'application

Indications d'application: Approved: Flo, IP, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or cells or 100 μL whole blood. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: TLR4

Sujet: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

ID gène: 7099

UniProt: O00206

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins